Vol. 3, Issue 3, 2012

α-Cellulose and microcrystalline cellulose powders, derived from agricultural waste products, were found to have similar flow characteristics as a commercial brand of microcrystalline cellulose suggesting that they could be a low-cost alternative for pharmaceutical binders or diluents.

Differential Scanning Calorimetry was used to study the interaction of new resveratrol derivatives using
dimyristoylphosphatidylcholine (DMPC) multilamellar vesicles (MLV) as biomembrane models. Results showed that the number and the position of the substituent strongly affected the
interaction between the compounds and the MLV based on DMPC.

While the ability of food ingredient mixtures or derivatives to modulate more of ‘delivery attributes’ should not be underestimated, a reevaluation of this paradigm is necessary such that ‘innovation by design’ supersedes ‘innovation by serendipity’, especially with regard to making pharmaceutical excipients fit for in vivo purpose.